CCMB-OU Study: Garlic prevents cataract in diabetics

July 25, 2008
By Syed Akbar
Hyderabad, July 24: Inclusion of garlic in daily dietary intake will prevent cataract, particularly the one related to diabetes.
A joint study by the department of zoology of Osmania University and the Centre for Cellular and Molecular Biology revealed that garlic had properties that would prevent the onset of cataract. The effect of garlic on cataract was more pronounced in the case of diabetics.
Thus far there's no potent therapeutic agent that could prevent or control the lens from opacification. Metabolic intervention through natural dietary ingredients like garlic will help in better management of the problem.
T Naga Raju and V Rajani Kanth of Osmania University and K Lavanya of CCMB carried out the research on rats.
"The ability of methanolic garlic extract in scavenging the transition metal ion-generated hydrogen peroxide reflected its antioxidant activity and indicated that it can prevent protein modifications mediated through metal-catalysed reactions in cataractous lenses," they said.

Garlic administration was found to normalise the glucose levels in a dose-dependent manner, suggesting its hypoglycemic (lower sugar levels) potential. The glycemic-mediated oxidative damage was countered by the garlic extract by delaying the progression of cataract.
Glycemic-induced stress is a major culprit contributing to oxidative insult that has far-reaching effects in diabetic cataract world-wide. And garlic being an antioxidant, it checks the growth of cataract.